Review/Commentary

Genes that distinguish physiological and pathological angiogenesis

/PMC/2007

Why It Matters

Identified 25 transcripts overexpressed in tumor endothelium that are not present in normal angiogenic tissue, demonstrating that physiological and pathological angiogenesis are molecularly distinct processes.

Key Findings

  • 25 gene transcripts found in tumor vessels that do not exist in normal healing tissue
  • Physiological and tumor angiogenesis are molecularly distinct processes