Preclinical (Animal)

Antiulcer activities of BPC-157 (PL-10, PLD-116), a novel gastric pentadecapeptide

Sikiric et al./PubMed/1993

Why It Matters

Original isolation of BPC-157 from human gastric juice. Demonstrated antiulcer properties in animal models. This is the foundational paper establishing BPC-157 as a human-derived peptide.

Key Findings

  • BPC-157 parent protein isolated from human gastric juice — it is an endogenous peptide
  • Demonstrated potent antiulcer activity across multiple animal models
Read the PaperPMID: 8298609